BioRoute
Find the right enzyme for your project in minutes, not months.
AI-powered search across 214M+ papers and 16+ databases. Get expression hosts, purification protocols, kinetics, and assay conditions -- extracted directly from the literature.
I want an enzyme that ...
Powering enzyme discovery at scale
How it works
From question to bench-ready protocol in three steps
Describe your enzyme need
Search in natural language -- by function, substrate, organism, temperature, or application. No keywords needed.
AI searches 16+ databases
BioRoute queries Semantic Scholar, OpenAlex, KEGG, UniProt, BRENDA, PubTator, ChEBI, STRING, Rhea, InterPro, IntAct, ChEMBL, PDB, AlphaFold, and Europe PMC simultaneously.
Get ranked candidates
Receive enzyme candidates ranked by evidence quality, with protocols, kinetics, and citations ready for the bench.
Capabilities
Built for researchers who need real data
Literature-grounded evidence
Every claim is traced to specific papers. No hallucinated data -- only verified findings from peer-reviewed sources.
Extended Data Sheet
Nine practical fields per candidate: thermostability, cofactors, substrate scope, pH optimum, expression host, solubility, inhibitors, activators, and storage conditions.
Cross-candidate intelligence
Domain architecture comparison, protein family grouping, and phylogenetic context across all candidates.
Protocol extraction
Methods sections extracted verbatim from full-text PDFs on demand -- expression, purification, assay conditions, and buffers. User-triggered, not automatic.
Kinetic parameters
Real Km, kcat, Vmax, and Ki values sourced from BRENDA with experimental conditions.
Lineage & domain analysis
Taxonomic lineage, conserved domain architecture, and InterPro family annotations for every candidate enzyme.
Ready to find your enzyme?
Describe what you need and let BioRoute do the literature search for you.
BioRoute searches specific databases and may not cover all published literature. Results should be verified against primary sources.